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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

Epic Games在网站Kotaku上发表的一份声明中则指出,提起法律诉讼的原因是罗杰斯在一个YouTube视频的可移除标签上写下了涉及DMCA的反诉内容,这段视频展示并推广了《堡垒之夜》外挂软件。
John Authers

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
From the themed collection: 首次买房需要看四点
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

他认为,地方政府通过卖地、强拆来追求GDP代价太大,早晚要还。“我愿意用一个政协委员的身份非常严肃地提出问题,我们是不是可以不要那么重视GDP?我们是不是可以选择减缓经济发展的速度?”
The survey discusses projections for going forward: "The cost of living is always changing and there are already indications of further changes that are set to take place during the coming year."

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
From the themed collection: 房企主打“现金为王”
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 大连香格里拉大酒店项目材秀
Open Access Perspective

Soft matter science and the COVID-19 pandemic

adj. 推测的,推理的,思索的,投机的

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

vt. 避免,逃避

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

单词complex 联想记忆:
这些排行榜是基于某个特定学科的研究能力而做出评价,与综合榜单评价方式不同。
James Bond 23 may still be quite a ways away from actually happening, as star Daniel Craig is commited to three chapters in the Millennium Trilogy, starting with the currently in-production The Girl with the Dragon Tattoo. There is currently no talk of hiring someone else to play James Bond, but if Craig is to reprise the role a third time, we still won't see James Bond 23 until 2014 at the earliest.
n. 校订,修正,修订本,复习

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

For once, the Lakers are in good spot and don't have to rush into anything. Take some time. See what they have. They're not making the playoffs with that defense, but that's not really the point of this season anyway.
5.星巴克。品牌喜爱度:26%/社交商务指数排名:26
多措并举降成本。
If you outsource any or all of your content writing, you need to make sure your content is original. Paste content into Copyscape’s analyzer tool, and you’ll instantly know whether the content is original.

Graphical abstract: Trends and targets in antiviral phototherapy
From the themed collection: 全国首套房贷平均利率连降四个月
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

贷款的条件不仅仅只局限于裸照。同样被泄露的还有大量疑似借贷双方对话的屏幕截图,一个贷款人要求女学生提供自己的自慰视频。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

The remaining of the top 10 were the University of Luxembourg (second), Ecole Polytechnique Federale de Lausanne (fourth), University of Geneva (fifth), ETH Zurich - Swiss Federal Institute of Technology Zurich (seventh), University of St. Gallen (eighth), National University of Singapore (ninth) and Imperial College London (10th).

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

calendar
4. 这事儿不能说太细。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

In early December, authorities announced that market circuit breakers would be introduced become effective from January 1 in an effort to limit the volatility seen during the savage, summer sell-off from June. The circuit breakers would see trading in shares, options and futures halted for 15 minutes if they fell by more than 5 per cent. On their first day of use, that first threshold was breached just after the return from the lunchbreak, prompting a 15-minute halt.
Venice has long been hailed as one of the most romantic cities in the world, a must-visit lagoon city on many people's travel lists.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Please accept my season\'s greetings.
Before becoming Germany's top trading partner, China was Germany's largest trading market in Asia. Germany has been China's top trading partner in the European Union for the last 2 years.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

目前,大部分围绕比特币的活动都是货币性的,因此,批评者指向其波动性也合乎情理。blockchain.info网站上的市场价格走势图显示,尽管以美元衡量的比特币价值在过去一年缩水了67%,其价值在过去两年则飙升了1879%。因此,投资比特币是好是坏,取决于你的视角。
Like a lot of critics, I chafe against the arbitrariness of lists even as I recognize their utility. Since I can never stop at 10 — how could I, when something like 900 movies were released in North American theaters? — I picked 15 to match the year, ranked them and ended up fudging that count. So maybe technically it’s a top 20. The slots with more than one title aren’t ties, but double features, paired movies that complement, contend with or amplify each other’s best qualities.
Tiger got to hunt, bird got to fly;
在这个被大型地产开发商主宰的市场,结构性挑战通常成为抑制欧美大型资产管理公司的因素。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

好在谷歌公司已于日前表示,他们不会让哈维尔支付这笔费用。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 美克家居联手苹果做智慧家居
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

“D型人格”最先由荷兰蒂尔堡大学的心理学家Johan Denollet提出。他还设计了一个测试,帮助人们认识自己是否具有D型人格特征。
Marlohe will shoot the Malick film concurrently with the ongoing press tour for Skyfall.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Wishing you all the blessings of a beautiful New Year season.愿你拥有新年所有美好的祝福。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Beijing is looking to unload excess reserves built up under the government’s subsidy policy.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 东莞住宅供应量降至年内低点
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

The Big Bang Theory is not short on geniuses. Not only is the show about highly intelligent scientists, but cast member Mayim Bialik has a Ph.D. in Neuroscience. So it should come as no surprise that the cast would want to show off their intelligence and attention to detail. In Sheldon and Leonard's apartment, there's a large white board. The two roommates use the board frequently for everything from actual work that Leonard or Sheldon has brought home, or to decide whether to eat before or after the new Spider-Man movie.
James Bond Themes 5. "Live and Let Die" by Paul McCartney and Wings
The system for ensuring responsibility is taken for poverty elimination will be effectively enforced, the strictest possible evaluations and assessments of poverty alleviation will be carried out, and stern measures will be taken to address deception, falsification, and the manipulation of numbers in poverty elimination work. We must see that the results of our poverty elimination earn the approval of our people and stand the test of time.
在针对已拥有金融业工作经验的学员开设的金融课程的排行榜上,伦敦商学院(London Business School)重新夺回在2011年至2015年占据的冠军宝座,同时英国剑桥大学(University of Cambridge)佳奇管理学院(Judge Business School)跌回第二名。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

包括中国移动、阿里巴巴和腾讯的16家中国企业进入了该榜单的前100名。
v. 撤退,向后倾
6. You dressed 10 times nicer than usual yesterday。
接受一份谋生型的工作有两个弊端。这样做会让你在求职中分心,而且潜在雇主对你以前的专业形象会有所怀疑。
This is BBC Sherlock, so your Watson isn’t stupid. He's rather smart in his own way and insecure about his sexuality (probably straight).

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

《泰晤士高等教育》专刊的编辑菲尔·巴蒂说道:“中国采取了强有力的政策,且背后又有雄厚的资金支持,才能打造这些世界一流的大学。2015年,中国就宣布将实施‘卓越计划',计划在2020年之前打造六所可以跻身世界一流行列的高校。”
Porto is nearly synonymous to port wine, and also its rich history. The city's historic center and the Alto Douro Wine Region have been listed as UNESCO World Heritage Sites.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

抓好金融体制改革。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Rogers, unhappy with the turn of events, decided to leave the show after the first three seasons. The breach of contract led to a multi-million dollar lawsuit. Ironically, Wayne Rogers had never signed his contract to begin with (he had a problem with a morals clause). The lawsuit was thrown out. You could say Rogers got the last laugh, but since M·A·S·H went on for eight more seasons and Rogers' never reached the same career success again, the last laugh might be a relative concept.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

While heavily dominated by French and English schools, accounting for 44 per cent of the table, the ranking is more diverse than ever with schools from 25 countries.
9.The Bling Ring
['t?nl]
Lu also said high-quality hospitals will be built in Tongzhou and new towns in other suburban districts to attract downtown residents and ease traffic jams and other congestions in crowded downtown areas.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

此外,去年共计新增银幕8035块,相当于每一天,都有22块银幕投入使用。现在全国共有大约31627块银幕。
On Monday night, Ankara confirmed that the Dutch ambassador would not be welcome to return to Turkey.
其造成的影响范围比中国数据失真要小。英国法律要求英国国家统计局计算RPI数据,鉴于该部门拒绝改善算法,这种数据造假行为影响了继续与RPI挂钩的总值达数千亿英镑的合同。
根据国内领先的求职平台前程无忧近日发布的一份关于2016年应届毕业生的研究报告显示,52.11%的高校毕业生已找到工作或自主创业。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

2.《洛奇》
['stre?θ?n]

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

对于很多西方白人来说,取得“获得性身份认同”(登上山巅)的机会似乎已经变得遥不可及。所以“先赋性身份认同”——也就是他们的“白”——变得比以往更加重要起来。
7.Morocco
将学习放在最重要的位置
A devastating financial crisis led business owners and corporate executives to be especially wary about adding staff or investing in new equipment. Some worry about risks from Washington or overseas. Others are seeing consumers maintain their slow-but-steady spending, providing little incentive to deploy their cash stockpiles.
请做好准备随时当他的救世主。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

3. How to lose weight
我们进行一个比较,佳士得和苏富比的这两次18世纪前绘画大师作品拍卖会共拍得2910万英镑,比五年前(2011年12月)类似拍卖会拍得的4420万英镑少了34%。
But Gitanjali's portable invention allows a sensor linked to a mobile app to give an accurate, almost immediate analysis.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
From the themed collection: 转战互联网+ 门窗电商是大势所趋
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Only Kobe Bryant had played in more games by age 32, and did so with fewer minutes, and that's just including regular-season games.
OUTDOOR SPACE: Steps down from the patio is a walled garden with a lawn and a fountain. The property is 0.10 acre.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 楼市错位去库存:大战才刚刚打响
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

3.Good problem solver
认为西方民主政体不会受影响将是愚蠢的。
el[=elect选择]+ite表名词,“人或物”…选出的人物→社会精英

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

现在对于宣传单张的内容还没有详细的介绍,但之前投放的传单都包含谴责北韩统治者家族的言论。
1.Photography: 22.3 percent increase
Here are the 10 winners of the 2012 Ig Nobel Prizes given to scientists, writers, and peacemakers who make silly but thoughtful contributions to the world, or as the Annals of Improbable Research puts it, "first make people laugh, and then make them think." I can vouch for them making us laugh!

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

亚太地区票房增长了13%,是推动国际票房增长的主力,而中国贡献了整个亚太地区近半票房。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

此外,广电总局还透露,虽然今年的票房增长受人民币贬值影响要稍低于35%,但是电影市场增长势头依旧强劲。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Directing for a Mini-Series or Movie: Susanne Bier, “The Night Manager”
单词foundation 联想记忆:

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

有7所商学院在过去一两年落榜后重新上榜。
Folk Song “Horse-Head Fiddle On A Deck”(Wang Hongwei)
Emily Ratajkowski managed to steal the show, opting for a seriously saucy twist on the classic ballgown. Opting for a semi-sheer lacey black number, the We Are Your Friends actress ensured her world-famous figure was on display.
20. 对电影爱好者的最佳建议。8月学者韦勒·温斯顿·迪克森(Wheeler Winston Dixon)发出了警告:“如果你上亚马逊,看到什么精彩的黑白电影卖三美元,或者其他什么外国电影和鲜为人知的电影,赶快买下来,因为它就要绝版了,他们不会再出版它们了。”成千上万这种VHS格式的电影不会被做成DVD格式或蓝光格式,迪克森警告说。而下载的美丽新世界(又名电子销售)明年将是好年头。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
From the themed collection: 定制家具 O2O模式迎合消费习惯
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

自从2010年开通运营以来,12306票务系统已多次升级以修复漏洞,并在春运期间提供更好的服务。
The people of both countries have the wisdom to properly manage their differences, there is a need and there are also conditions for us to continue to expand our common interests.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

这确实是的。不过费城队近年来如此努力地垫底的一个被忽略的好处是:他们是如此地烂,以至于这会让其他竞相垫底的球队产生挫败感,因为他们很难做到和76人一样烂。在76人面前,小牛队至少只能算是中等水平的烂。
n. 全体船员,全体乘务员,(一组)工作人员

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

I have never ordered an ice bucket for my red wine. In fact, come to think of it, I have never ordered an ice bucket for white wine, Champagne or dessert wine.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

At tech start-up conferences, such as Slush in Helsinki in December, everyone was talking about experiences. The coming year is likely to see a wider adoption of virtual reality, which places the user in a digitally enhanced environment, and augmented reality, which overlays digital information on to the real world, creating new digital businesses.
业内人士称,该调查显示我国正在进行产业升级,高附加值的服务行业呈上升趋势,这将带来一个欣欣向荣、需要理工类专业人才的互联网产业和一个蒸蒸日上、需要财经类专业人才的金融产业。
公民价值观是民主政体最重要的资产。
Even though we are apart, you are in my heart this season.千山万水,隔不断我在佳节对你的思念。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

Ultimately, democracy, or a democratic republic, provides a way for people with different views and even cultures to live side by side in reasonable harmony.
There are 27 companies that are dropped from the list this year, including AT&T, IBM, Siemens and Xerox.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

9. Smart wine bottle
"某时,世界呈现给我们是相互分隔的,但是这些电影和电视作品让我们感觉世界是相通的,"美国电影学院的总裁兼首席执行官Bob Gazzale如是说。"美国电影学院奖表彰这些电影艺术家们,勇于挑战,让我们受到鼓舞,娱乐,又励志,最后让我们意识到,我们都有着同样的心跳,"
锁定一个品牌,它擅长于制作你想要的类型的车,这样可以高效地购买并找到对你来说最好的车。2016美国新闻最佳汽车品牌奖从四个类别挑选了最佳的品牌:轿车、SUV、卡车和豪车。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

"Last year, 1.2 million Chinese visited Australia. We anticipate this will grow during the China-Australia Year of Tourism and will continue to grow afterward."
I'm not worried about Philly, Phoenix, or Minnesota. They're young, they're rebuilding. If they make strides, great. If not, take another high pick. The Nets are the Nets and we should talk about them in a minute.
In month-on-month terms, consumer prices fell 0.1 per cent after having risen 0.7 per cent a month earlier.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

如果一个“推文幼稚的像个幼儿园小朋友”一样最年长的人,都可以当选总统,那为什么反过来不试一下,看看年轻人能否当选并明智地执政?
据另一家市场研究公司Counterpoint的统计数据显示,中国去年智能手机总出货量达到了4.65亿台,占据全球总量的近三分之一。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

根据《重庆晨报》报道,今年4月24日,这名16岁的周姓同学将农药倒入了教室的饮水机中,显然是在报复扰乱课堂秩序、影响自己学习的同学们。
在一份电邮声明中,国际足联表示,在小组赛中,三等票总计售出143364张,相当于每场比赛就卖出了3000张。
The renewal of the 70-year term of land-use rights by urban-dwelling owners will be no problem. No application needs to be filed, there will be no preset conditions and it will not affect any deal being made over the property.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

3. Will Guo Jingjing, China's diving queen, get married in 2010?
Hidrate Spark 2会通过移动App跟踪你的水摄入量和记录你一天喝了多少盎司的水,还可以根据在有盎司数标识的水瓶里灌了几次水来跟踪你的饮水量。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 长租公寓 缘何租金高却一房难求
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

My favourite award every year is for a spurious renaming of a common noun. A couple of years ago, Speedo rechristened the swimming cap a “hair management system”. Last year, Falke went one better by renaming a line of socks “Life Performance Solutions”.
该项调研还显示,会计与金融专业的毕业生也将走俏。那些已在为明年夏天毕业后的生路做打算的学生们需要谨记:上述调研中,有52%的受访雇主表示,他们更愿意雇佣有实习经验的毕业生。
In my anger, I am not blind, and in my fear, I am not afraid to tell the world how I feel. 然而事实却让我很愤怒,但我也很清醒,我虽然害怕,但我敢于告诉世界我真实的感受。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
From the themed collection: 楼价连升25个月 香港或开征空置税
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Hurun Chairman Rupert Hoogewerf said: "Those entrepreneurs should be called 'super wealth creators' instead of simply 'rich people', which could highlight their contribution to China's society and economy."

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
From the themed collection: 京津冀将现“1小时通勤圈”
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

WOLF HALL (PBS, April 5) In the season’s most promising piece of casting, Damian Lewis (“Homeland”) will play Henry VIII and the two-time Tony Award winner Mark Rylance will play Thomas Cromwell in this “Masterpiece” adaptation of the popular Hilary Mantel historical novels.
住房市场能轻松适应利率上升吗?

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Sweden’s foreign minister, Margot Wallstrom, a proponent of a “feminist foreign policy,” opened up to Ellen Barry about her abuse at the hands of an old boyfriend when she was a young woman, something she had never said publicly before.
v. 引诱,吸引

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Revenge epic The Revenant was named best drama picture and DiCaprio and Inarritu walked to the stage to collect it together.
This is second major English-language role for the French actress, who co-stars opposite Daniel Craig in Skyfall as the enigmatic Severine. The movie opens Nov. 9 in North America but already is shattering records internationally.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

6. 查理兹-塞隆 1650万美元
今年剩余时间将是大西洋两岸首次公开发行(IPO)的繁忙季节,意大利倍耐力(Pirelli)(见题图)、阿里巴巴(Alibaba)支持的百世物流(Best Logistics)和视频流媒体平台Roku等公司都将上市。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

Harvard topped the league table, followed by Massachusetts Institute of Technology and Stanford University.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Will Smith had a very successful career in the late 80s and early 90s as the second half of rap duo DJ Jazzy Jeff and the Fresh Prince. But in spite of his financial success, Smith did not manage his money well. It's a pretty classic tale, really. New fame, lots of money, no future plans, and lots of fancy toys added up to a lot of overspending. This lack of oversight and fiscal irresponsibility landed him on the brink of bankruptcy. He owed the government back taxes that he had not paid.
预计新一代iPhone中,将至少有一款采用人脸识别技术,这种图像捕捉技术能够感知深度,并追踪人脸及表情。随着苹果与Facebook和Snapchat等公司争夺用户的关注度,新一代iPhone将增加一系列包括猴子和机器人的新表情符号,其动画表情能够反映iPhone用户的脸。
Cross talk (Guo Degang and Yu Qian)
Major areas of work for 2017

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

我们的外汇储备是充裕的,是足以支付进口和满足短期偿债需要的。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

"The Hunger Games" star ranks first on the 2012 edition of AskMen.com's "Top 99 Most Desirable Women" list. The poll, which collected more than 2.4 million votes, asked the website's readers to choose their favorite female celebrities based on their looks, personality, talent and other desirable characteristics.
global
In P2P lending, borrowers are matched with investors, who are encouraged to put their money into the loans due to higher returns than they could get at state banks.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

从技术上来说,这是东盟(ASEAN)十个成员国将本地区所有贸易协议纳入一个整体框架的计划。它也没有TPP在许多方面的雄心。
7、Bad body language habits

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

相比之下,新兴市场出口的平均单价差不多自2012年中以来就一直呈同比下降趋势,2016年2月同比降幅达到16.4%。
4. OPEC’s Next Move.OPEC deserves a lot of credit (or blame) for the remarkable downturn in oil prices last year.While many pundits have declared OPEC irrelevant after their decision to leave output unchanged, the mere fact that oil prices crashed after the cartel’s November meeting demonstrates just how influential they are over price swings. For now OPEC – or, more accurately, Saudi Arabia – has stood firm in its insistence not to cut production quotas. Whether that remains true through 2015 is up in the air.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

“Today you have to shop by image,” Mr. Nathan said. “But if you are brave and don’t follow fashion, there are opportunities.”

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Apple Inc., Alphabet Inc.'s Google, and Coca-Cola Co. topped the list of the world's 100 most valuable brands in 2016, while technology and automotive brands dominated the overall rankings, according to a new report from brand consultancy Interbrand.
It was all work, work, work for the BBC Culture team and parties, alas, were few and far between. But the rest of Cannes was painting the town red. In 2013 we tried to calculate the amount of champagne consumed at the festival by contacting Piper Heidsieck, “the official drink” of the festival, but they declined to comment – though judging by the merry faces and staggering gaits of some on the Croisette, it's safe to assume a colossal quantity. At the party for Matteo Garrone's Tale of Tales on the first weekend, the champers flowed freely and the revellers stayed on until the early hours. When the BBC's Rebecca Laurence spoke to one of its stars the following morning and asked how many hours sleep he'd had before their interview, he simply narrowed his bleary eyes and held up two fingers.
The results are based on a survey of 15,870 people across the country in August and September.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

The continued, albeit slower growth in prices tracks with recent data showing real estate investment ticked upward in October and sales had registered barely any negative impact from the new restrictions.
外部事件的影响。《消费者报告》(Consumer Reports)杂志曾经对Model S大加吹捧,但最近该杂志也报道了它的一些常见故障,包括门把手失效,中控触屏白屏,导致车内大部分功能不能使用等等。汽车网站Edmunds.com也找了Model S的麻烦。更多此类报告无疑会影响特斯拉到目前为止非常正面的声誉。
节目7 歌曲《春暖花开》,那英
“当前是经济动荡时期,但我们看到中国企业满怀信心地行动,继续在欧洲和北美做出大动作,”他说。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

The US has overtaken India as the leading user of anti-dumping and other trade defence cases, with China and its steel sector the biggest target, according to research.
With the majority of professional advisors (myself included) preaching the benefits of global diversification to their clients, 2014 looks more like a draw than an outright victory in the harsh light of December’s low winter sun. Consider the fact that, through last week, the MSCI World Index gained just 2% on the year, with nearly 5% drops for both the MSCI Emerging Markets index and the EAFE index of developed markets outside of the United States. Ironically, the single best-performing foreign market in the world, the Shanghai Composite of mainland Chinese equities (up 45%) is the only one that U.S. investors could not actually put their money into.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 通州建人才产业园服务京津冀
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

若原油供应严重中断,仍可能会推高油价,但潜在的供应过剩会降低这种可能性。Saxo Bank的大宗商品策略部门主管汉森(Ole Hansen)说,新兴市场的需求曾使得供应如此紧张,因而任何一次供应中断都造成了油价的大幅波动。
香港科技大学(Hong Kong University of Science and Technology)和凯洛格管理学院(Kellogg School of Management)合办的中美EMBA项目重新夺回英国《金融时报》100个最佳EMBA项目排行榜的冠军宝座。
Fifty-two colleges and universities across 11 provinces in China are equipped with vending machines that sell AIDS detection reagent for students to conduct self-examinations.

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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The data showed that Samsung took the top spot, followed by Apple in second place. Even so, the shipments of the two top tech giants declined respectively by 3 percent and 7 percent, demonstrating decreased global market shares.
Lei Jun, founder and chairman of Chinese smartphone giant Xiaomi Corp, agreed, describing the win as a breakthrough in artificial intelligence.

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